Back
Episode 33

Legal Issues in the Gene Editing Space: Lisa Taylor Ash, General Counsel at Shape Therapeutics

Episode summary

Introduction: 0:00

  • Introducing Lisa Taylor Ash, General Counsel of Shape Therapeutics. 
  • Merging a deep passion for science with law to forge a career as a biotech GC.

Leading legal through two major acquisitions: 2:48

  • Folding Pharmacyclics into Abbvie and Juno Therapeutics into Celgene.
  • Representing the smaller company in an M&A process.
  • Positioning your company as the expert on the product and its related legal concerns.
  • Trusting your own experience with the product and regulations.

Developing personalized medicines: 8:56

  • Breaking down the decades-long process from research to innovative medical breakthroughs.

Lessons for lawyers dealing with M&A: 12:11

  • Recognizing that legal issues rarely impact deal dynamics.
  • Emphasizing clarity with your business partners.
  • Advocating for your company’s expertise and established policies.

Leaving large companies after an acquisition: 14:06

  • Favoring small biotech companies because of their position at the forefront of cutting edge science.
  • Gaining the ability to work on all legal-related aspects of a product.

Launching an independent consulting firm: 15:51

  • Converting your expertise and experience about biotech and healthcare law into a business. 
  • Preferring the consultant relationship over one in which you offer legal advice.
  • Working with forty different healthcare companies over an eighteen-month period.
  • Calling on your network and venture capital to build a client list.

Offering practical advice for starting a consulting business: 19:39

  • Moving forward with your plan regardless of whether you have GC experience.
  • Trusting your gut on who you should or should not work with.
  • Assessing the value and establishing longterm relationships.
  • Building your confidence and prioritising directness.
  • Taking equity versus charging an hourly rate.

Returning to an in-house role at Shape Therapeutics: 24:37

  • Valuing the variety of working experiences in consulting but preferring the depth of in-house work.
  • Explaining the science behind RNA programming at Shape Therapeutics and the developing field of personalized medicine.

Legal issues related to gene editing: 30:47

  • Reshaping a drug development and regulatory framework to deal with individual questions of personalized medicine. 
  • Working with the FDA and global regulatory authorities to create new frameworks for patients.

Building public trust in gene therapy companies: 32:57

  • Cooperating with regulatory authorities and developing new systems for informed consent.
  • Dealing with AI-related questions surrounding privacy, IP rights, trade secrets, and legal and ethical issues.

The future of AI and gene editing: 35:41

  • Bolstering rapid experimentation and finding solutions that humans may not have considered.
  • Bringing biology and computer science together.

Creating an essential legal resource at effectiveinhouse.com: 36:51

  • Identifying repeating themes and issues working in-house at different companies.
  • Emphasizing the importance of understanding and being a partner in the business.
  • Offering a resource to share core lessons and answer important questions.
  • Getting a chance to interview other lawyers and share their experiences.
  • Exposing young lawyers to what it means to be an in-house lawyer.

Book Recommendations: 41:35

  • The Effective Executive by Peter Drucker
  • Anything by Adam Grant
  • High: A Journey Across the Himalaya, Through Pakistan, India, Bhutan, Nepal, and China by Erika Fatland
  • Dune by Frank Herbert

What you wish you had known as a young lawyer: 44:03

  • Understanding that there is a different path forward than writing legal briefs for lawyers interested in business problems.

View more
Host
Tyler Finn
Head of Community & Growth, SpotDraft
Guest
Lisa Taylor Ash
General Counsel, Shape Therapeutics

More episodes coming soon

Subscribe to hear from the biggest voices in legal.

Tell me when new episodes are out

AVAILABLE ON
Back
Episode 33

Legal Issues in the Gene Editing Space: Lisa Taylor Ash, General Counsel at Shape Therapeutics

In this episode

Host
Tyler Finn
Head of Community & Growth, SpotDraft
Guest
Lisa Taylor Ash
General Counsel, Shape Therapeutics

Summary

Introduction: 0:00

  • Introducing Lisa Taylor Ash, General Counsel of Shape Therapeutics. 
  • Merging a deep passion for science with law to forge a career as a biotech GC.

Leading legal through two major acquisitions: 2:48

  • Folding Pharmacyclics into Abbvie and Juno Therapeutics into Celgene.
  • Representing the smaller company in an M&A process.
  • Positioning your company as the expert on the product and its related legal concerns.
  • Trusting your own experience with the product and regulations.

Developing personalized medicines: 8:56

  • Breaking down the decades-long process from research to innovative medical breakthroughs.

Lessons for lawyers dealing with M&A: 12:11

  • Recognizing that legal issues rarely impact deal dynamics.
  • Emphasizing clarity with your business partners.
  • Advocating for your company’s expertise and established policies.

Leaving large companies after an acquisition: 14:06

  • Favoring small biotech companies because of their position at the forefront of cutting edge science.
  • Gaining the ability to work on all legal-related aspects of a product.

Launching an independent consulting firm: 15:51

  • Converting your expertise and experience about biotech and healthcare law into a business. 
  • Preferring the consultant relationship over one in which you offer legal advice.
  • Working with forty different healthcare companies over an eighteen-month period.
  • Calling on your network and venture capital to build a client list.

Offering practical advice for starting a consulting business: 19:39

  • Moving forward with your plan regardless of whether you have GC experience.
  • Trusting your gut on who you should or should not work with.
  • Assessing the value and establishing longterm relationships.
  • Building your confidence and prioritising directness.
  • Taking equity versus charging an hourly rate.

Returning to an in-house role at Shape Therapeutics: 24:37

  • Valuing the variety of working experiences in consulting but preferring the depth of in-house work.
  • Explaining the science behind RNA programming at Shape Therapeutics and the developing field of personalized medicine.

Legal issues related to gene editing: 30:47

  • Reshaping a drug development and regulatory framework to deal with individual questions of personalized medicine. 
  • Working with the FDA and global regulatory authorities to create new frameworks for patients.

Building public trust in gene therapy companies: 32:57

  • Cooperating with regulatory authorities and developing new systems for informed consent.
  • Dealing with AI-related questions surrounding privacy, IP rights, trade secrets, and legal and ethical issues.

The future of AI and gene editing: 35:41

  • Bolstering rapid experimentation and finding solutions that humans may not have considered.
  • Bringing biology and computer science together.

Creating an essential legal resource at effectiveinhouse.com: 36:51

  • Identifying repeating themes and issues working in-house at different companies.
  • Emphasizing the importance of understanding and being a partner in the business.
  • Offering a resource to share core lessons and answer important questions.
  • Getting a chance to interview other lawyers and share their experiences.
  • Exposing young lawyers to what it means to be an in-house lawyer.

Book Recommendations: 41:35

  • The Effective Executive by Peter Drucker
  • Anything by Adam Grant
  • High: A Journey Across the Himalaya, Through Pakistan, India, Bhutan, Nepal, and China by Erika Fatland
  • Dune by Frank Herbert

What you wish you had known as a young lawyer: 44:03

  • Understanding that there is a different path forward than writing legal briefs for lawyers interested in business problems.

Related podcasts